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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AURKB
All Species:
36.06
Human Site:
S222
Identified Species:
61.03
UniProt:
Q96GD4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96GD4
NP_004208.2
344
39280
S222
K
I
A
D
F
G
W
S
V
H
A
P
S
L
R
Chimpanzee
Pan troglodytes
XP_511856
395
44529
S273
K
I
A
D
F
G
W
S
V
H
A
P
S
L
R
Rhesus Macaque
Macaca mulatta
XP_001118154
562
62706
S440
K
I
A
D
F
G
W
S
V
H
A
P
S
L
R
Dog
Lupus familis
XP_849906
346
39574
H224
A
D
F
G
W
S
V
H
A
P
S
L
R
G
R
Cat
Felis silvestris
Mouse
Mus musculus
O70126
345
39306
S227
K
I
A
D
F
G
W
S
V
H
A
P
S
L
R
Rat
Rattus norvegicus
O55099
343
39216
S225
K
I
A
D
F
G
W
S
V
H
A
P
S
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521399
303
34973
T187
A
P
S
S
R
R
T
T
L
C
G
T
L
D
Y
Chicken
Gallus gallus
XP_425725
409
46456
S292
K
I
A
D
F
G
W
S
V
H
A
P
S
S
R
Frog
Xenopus laevis
Q6DE08
361
41717
S238
K
I
A
D
F
G
W
S
V
H
A
P
S
L
R
Zebra Danio
Brachydanio rerio
Q6NW76
320
36928
S198
K
I
A
D
F
G
W
S
V
H
A
P
S
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKN7
329
38282
S200
K
L
A
D
F
G
W
S
A
H
T
P
N
N
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01427
305
34731
P194
C
G
T
M
D
Y
L
P
P
E
M
V
N
G
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M077
294
33954
R183
S
V
H
T
F
N
R
R
R
T
M
C
G
T
L
Baker's Yeast
Sacchar. cerevisiae
P38991
367
42927
I250
L
T
D
F
G
W
S
I
I
N
P
P
E
N
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
60.3
91.3
N.A.
84.9
84.5
N.A.
61.9
56.9
67.5
66.5
N.A.
44.4
N.A.
53.4
N.A.
Protein Similarity:
100
86.3
60.6
95
N.A.
91.5
90.4
N.A.
72
66.5
78.6
76.1
N.A.
62.5
N.A.
65.1
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
0
93.3
100
100
N.A.
60
N.A.
0
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
20
93.3
100
100
N.A.
80
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.9
36.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68
59.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
65
0
0
0
0
0
15
0
58
0
0
0
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% C
% Asp:
0
8
8
65
8
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% E
% Phe:
0
0
8
8
72
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
8
8
65
0
0
0
0
8
0
8
15
0
% G
% His:
0
0
8
0
0
0
0
8
0
65
0
0
0
0
0
% H
% Ile:
0
58
0
0
0
0
0
8
8
0
0
0
0
0
0
% I
% Lys:
65
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
8
8
0
0
0
0
8
0
8
0
0
8
8
50
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
15
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
8
0
0
15
15
0
% N
% Pro:
0
8
0
0
0
0
0
8
8
8
8
72
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
8
8
8
8
0
0
0
8
0
72
% R
% Ser:
8
0
8
8
0
8
8
65
0
0
8
0
58
8
0
% S
% Thr:
0
8
8
8
0
0
8
8
0
8
8
8
0
8
0
% T
% Val:
0
8
0
0
0
0
8
0
58
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
8
8
65
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _